ANTIMICROBIAL STEWARDSHIP ENGINE

Antibiotic Resistance Checker & Risk Calculator

Evaluate antimicrobial treatment failure probability and drug-resistant bacterial infection risk. Powered by WHO AWaRe stewardship guidelines, historical broad-spectrum exposure analysis, and inflammatory laboratory biomarkers (WBC, CRP, Procalcitonin).

Calculates Resistance Risk Score (0–100) Identifies ESBL & MRSA Red Flags No Registration Required

Patient Clinical History

Basic Demographics

Patient Name / ID (Optional)

Age Group *

Antibiotic Exposure & Symptom Timeline

Prior Exposure

Fever Duration *

Antibiotics Taken in the Last 90 Days (Select All That Apply)

Azithromycin / Erythromycin Ciprofloxacin / Levofloxacin Cefixime / Ceftriaxone Amoxicillin / Augmentin Doxycycline / Tetracycline No Prior Antibiotics

Laboratory Inflammatory Biomarkers

Optional CBC/CRP

WBC Count (cells/mcL)

Neutrophil Percentage (%)

C-Reactive Protein (CRP) (mg/L)

Procalcitonin (ng/mL)

Suspected Primary Infection Site *

Awaiting Clinical Inputs

Fill out the patient details and prior antibiotic exposure form on the left to calculate the Antimicrobial Resistance Risk Score.

WHO AWaRe Stewardship Compliance

Why Broad-Spectrum History Matters

Repeated use of fluoroquinolones (Ciprofloxacin) or 3rd-gen cephalosporins (Cefixime) creates selective pressure, increasing odds of ESBL-producing enterobacteriaceae or MRSA colonization by over 3.4x.

Understanding Antimicrobial Resistance (AMR) & Clinical Biomarkers

Antimicrobial Resistance occurs when bacteria evolve to withstand medications designed to eliminate them. When first-line antibiotics fail due to resistance, treatments become less effective, leading to prolonged illness, higher healthcare costs, and elevated mortality.

Prior Antibiotic Exposure

Patients taking broad-spectrum antibiotics within 90 days harbor altered microbiome flora, giving resistant strains competitive advantage over susceptible organisms.

WBC & Neutrophil Shift

Leukocytosis (WBC >12,000 cells/mcL) combined with a left-shift (neutrophils >80%) indicates acute bacterial burden requiring immediate targeted bactericidal therapy.

CRP & Procalcitonin

Elevated Procalcitonin (>0.5 ng/mL) specifically differentiates severe bacterial infection from viral origin, preventing unnecessary antibiotic overprescribing.

Need Bedside Vital Deterioration Monitoring?

Assess MEWS scores and early sepsis alerts for emergency ward admissions.

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